Articles tagged Model Organisms
(72 results)

Fascinating discoveries sometimes emerge from the most daunting of experimental roadblocks. Designed to generate over 1,000 recombinant inbred mice lines for genetic mapping, the Collaborative Cross (CC) project unearthed astounding variation in male fertility when nearly 95% of the highly inbred CC lines went extinct. As part of the Multiparental Populations series in the June…

Illuminating the cover of the May issue of G3 is a lake-dwelling filter feeder no more than a couple millimeters long. This microcrustacean—Daphnia pulex, also known as the water flea—is an important model organism, especially in ecological genetics. But despite Daphnia’s status as a model organism, no one had examined its population genomics until now.…

Thanks to more than a hundred years of working with Drosophila melanogaster, geneticists have many powerful tools for precisely manipulating its genes. It has also become a model system for studying speciation and molecular evolution together with the other members of the melanogaster species group: D. simulans, D. mauritiana, D. yakuba, and D. santomea. However,…

In 1997, Ahna Skop approached her graduate advisor, John G. White, about adding a worm-themed art show to the International C. elegans Conference he was organizing that year. “He said I could do whatever I wanted, but not to involve him,” she recalls. That year marked the very first Worm Art Show, which has since…

Why are scientists so interested in the health of seemingly insignificant creepy crawlies, vermin, microscopic blobs, and spindly weeds? This question is considered in a guest post up today on the March for Science blog by GSA Communications Director Cristy Gelling and University of California, Berkeley grad student Nicole Haloupek. Artist and Sanger Institute postdoc Alex…

In the genomic era, population geneticists are flooded with molecular data on the evolution of natural populations. This deluge started in 1966 as a trickle of data from protein electrophoresis studies, including the landmark GENETICS papers published by Richard Lewontin and John Hubby. As Lewontin is honored this week at the Annual Drosophila Research Conference…

These worms are as long as a pencil’s tip and only just visible without a microscope. They are among the smallest multicellular animals, but they still have complex organ systems. They are Caenorhabditis elegans, one of the most important organisms in modern biology and a key to understanding the most basic molecular processes of life.…

Each year, emergency departments in the US treat almost 700,000 people for traumatic brain injury (TBI). The outcome depends largely on the severity and location of the injury, but these aren’t the only factors. Age also plays a role, with children often recovering more fully than do adults. The patient’s diet following the injury may…

The human brain is an amazing machine powered by electricity. Carefully controlled patterns of changing electrical charges in neurons allow us to to think, move, and speak. When this system is disrupted, very bad things happen. A seizure occurs when a sudden surge of electrical activity in the brain interrupts normal functioning. Seizures are accompanied…

The Allied Genetics Conference was a combined meeting of seven genetics research communities held July 13-17, 2016 in Orlando, Florida. Many talks given throughout the meeting featured compelling images and videos that generated a lot of buzz in various communities. Here, Genes to Genomes is excited to highlight just a few of the wonderful scientific images shared at #TAGC16.…

Guest post by the Alliance of Genome Resources. If you want to help the Alliance please take a short survey at: https://www.surveymonkey.com/r/GSA-AllianceSurvey Six of the founding members of the Alliance of Genome Resources (Saccharomyces Genome Database, WormBase, FlyBase, Zebrafish Model Organism Database, Mouse Genome Database and the Gene Ontology Consortium) attended GSA’s The Allied Genetics…