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Articles tagged Population Genetics
(66 results)
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Inbred Neanderthals left humans a genetic burden
The Neanderthal genome included harmful mutations that made the hominids around 40% less reproductively fit than modern humans, according to estimates published in the latest issue of GENETICS. Non-African humans inherited some of this genetic burden when they interbred with Neanderthals, though much of it has been lost over time. The results suggest that these harmful…
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First gene linked to temperature-dependent sex determination
The sex of many reptile species is set by temperature. New research reported in the journal GENETICS identifies the first gene associated with temperature-dependent sex determination in any reptile. Variation at this gene in snapping turtles contributes to geographic differences in the way sex ratio is influenced by temperature. Understanding the genetics of sex determination…
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Dobzhansky: Bug collecting and the Modern Synthesis
In 1917, amidst the turmoil of the Russian Revolution, a bug-obsessed teenager in Kiev discovered a new species of ladybird beetle in the debris washed up on the banks of the flooding Dnieper River. The following year, he described the species in his first scientific publication. That 18-year old ladybug spotter —Theodosius Dobzhansky— would go…
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Sewall Wright: Evolving Mendel
In 1931, Sewall Wright—a quiet American geneticist specializing in livestock and guinea pigs—published a GENETICS paper that changed how we study evolution. Wright’s “Evolution in Mendelian populations” was one of the founding documents of population genetics and was among the first formal frameworks to reconcile Mendel’s laws of inheritance with Darwin’s vision of natural selection.…
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The evolution of Dark-fly
On November 11, 1954, Syuiti Mori turned out the lights on a small group of fruit flies. More than sixty years later, the descendents of those flies have adapted to life without light. These flies—a variety now known as “Dark-fly”—outcompete their light-loving cousins when they live together in constant darkness, according to research reported in…
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Mapping structural variants with nanochannel arrays
Short-read sequencing has fueled the acceleration of genetic research But though these next-generation methods are fast and efficient, they can’t do everything well. One important area in which short-reads fall short is detecting structural variants (SV), where chunks of the genome are deleted, inserted, repeated, inverted, or in some other way shuffled around compared to…
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New Faculty Profile: Erik Andersen
New Faculty Profiles showcase GSA members who are establishing their first independent labs. If you’d like to be considered for a profile, please complete this form on the GSA website. Erik Andersen Assistant Professor of Molecular Biosciences (Since 2013) Northwestern University Lab website Personal Twitter: @ecandersen Research program: My lab has broad interests…
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Working through the issues: Science, ethics and governance of gene drive research
The Committee on Gene Drive Research in Non-Human Organisms convened by National Academies of Sciences, Engineering, and Medicine held an information gathering meeting on October 28, 2015, to consider the Science, Ethics and Governance Considerations for Gene Drive Research. This meeting comes as a component of a large Gene Drive study, which is set to review the…
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Modeling the promise and peril of gene drive
What if we could eradicate malaria by engineering a mosquito population that doesn’t transmit the disease? What if we could control invasive species that outcompete natural populations? What if we could get rid of insecticide-resistant pests not by developing new chemical treatments, but instead by changing the population itself and driving it toward extinction? Although…
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Using evolution to link genes and behavior
Genes to Genomes asked Dr. Carolyn (Lindy) McBride (Princeton University), a recipient of the Rosalind Franklin Award for Young Investigators, to tell us about her research and what it means to receive the award. She was recognized for her Rosalind Franklin Award along with another recipient, Dr. Maria Barna, at the 2015 American Society of Human Genetics…
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Biotechnology Regulations to be Updated
The federal regulatory policy in use today for biotechnology products, known as the Coordinated Framework for the Regulation of Biotechnology, was created in 1986 through a joint effort between the U.S. Department of Agriculture (USDA), the Environmental Protection Agency (EPA), the Food and Drug Administration (FDA), the National Institutes of Health (NIH), the National Science Foundation…