Articles tagged Genetics Journal
(248 results)

In the genomic era, population geneticists are flooded with molecular data on the evolution of natural populations. This deluge started in 1966 as a trickle of data from protein electrophoresis studies, including the landmark GENETICS papers published by Richard Lewontin and John Hubby. As Lewontin is honored this week at the Annual Drosophila Research Conference…

One of the last places you’d expect to find a charged amino acid residue is buried within the hydrophobic interior of a lipid bilayer. And for the most part, this expectation holds true: portions of proteins that span membranes are typically composed of hydrophobic residues. But in some cases, the positively charged residues lysine and…

Check out the March issue of GENETICS by looking at the highlights or the full table of contents! ISSUE HIGHLIGHTS Simultaneous modeling of disease status and clinical phenotypes to increase power in genome-wide association studies, pp. 1041-1047 Michael Bilow, Fernando Crespo, Zhicheng Pan, Eleazar Eskin, and Susana Eyheramendy Jointly modeling clinical phenotype and disease status is a promising…

Fruit fly larvae have one goal: eat as much as possible. After the tiny worm-like larvae hatch from eggs embedded into the flesh of rotting fruit, they eat their way out. After days of gorging, they find a good spot to pupate and then emerge as adults. Fruit flies cannot grow after this transformation, however,…

When geneticist Rob Unckless took his son to Lego Club at the local library, he was not expecting to start a new collaboration. The result is the striking piece of science-inspired art that graces the cover of the February issue of GENETICS. Created by artist Kent Smith, “Attack of the 50 Foot Mosquito” was inspired…

Despite being covered by a massive, permanent ice sheet, Greenland has been continuously inhabited by humans for over a thousand years. Most modern Greenlanders are Inuit whose ancestors migrated eastward from Canada around 1000 AD, bringing technology like kayaks and dogsleds. They eventually settled on the coasts of the world’s largest island, hunting whales and…

The arms race between pathogens and their hosts leaves clear genetic marks: the most quickly evolving parts of host genomes often include immune genes. But are these fast-movers the exception among immune genes, or do most genes in this class bear the genetic signature of strong selection? In the January issue of GENETICS, Early et…

Check out the February issue of GENETICS by looking at the highlights or the full table of contents! ISSUE HIGHLIGHTS Feeding-related traits are affected by dosage of the foraging gene in Drosophila melanogaster, pp. 761-773 Aaron M. Allen, Ina Anreiter, Megan C. Neville, and Marla B. Sokolowski The foraging gene has been implicated in multiple feeding-related traits. Allen…

Well over 15,000 years ago, a man and a bear died in a cave in the Jura Mountains in modern-day Switzerland. That was the end of the story for millennia—until their remains were discovered in 1954 by researchers investigating the cave. Further work in the 1990s uncovered the fact that the man had, in fact,…

Check out the January issue of GENETICS by looking at the highlights or the full table of contents! ISSUE HIGHLIGHTS This Month’s Centennial Articles The sustained impact of model organisms—in genetics and epigenetics, pp. 1-4 Nancy M. Bonini and Shelley L. Berger In this GENETICS Centennial commentary, Nancy M. Bonini and Shelley L. Berger reflect on the history of…

These worms are as long as a pencil’s tip and only just visible without a microscope. They are among the smallest multicellular animals, but they still have complex organ systems. They are Caenorhabditis elegans, one of the most important organisms in modern biology and a key to understanding the most basic molecular processes of life.…