The GSA Journals, GENETICS and G3: Genes|Genomes|Genetics, are proud to present our annual Spotlight booklets for research published in 2016. Each Spotlight is a showcase of the excellent research and scholarship published over the course of the year, along with a selection of striking images submitted by our authors.

Browse the 2016 GENETICS Spotlight.

Browse the 2016 G3 Spotlight.



Degradation of the Mitotic Cyclin Clb3 Is not Required for Mitotic Exit but Is Necessary for GCyclin Control of the Succeeding Cell Cycle

Kresti Pecani and Frederick R. Cross

Genetics December 2016 204:1479–1494



The Genetic Cost of Neanderthal Introgression

Kelley Harris and Rasmus Nielsen

Genetics June 2016 203: 881-891



Evolution of Schooling Behavior in Threespine Sticklebacks Is Shaped by the Eda Gene

Anna K. Greenwood, Margaret G. Mills, Abigail R. Wark, Sophie L. Archambeault, and  Catherine L. Peichel

Genetics June 2016 203: 677–681



Maternal MEMI Promotes Female Meiosis II in Response to Fertilization in Caenorhabditis elegans

Maryam Ataeian, Justus Tegha-Dunghu, Donna G. Curtis, Ellen M. E. Sykes, Ashkan Nozohourmehrabad, Megha Bajaj, Karen Cheung, and Martin Srayko

Genetics December 2016 204: 1461–1477


Commentary: Parental Control Begins at the Beginning

Diana Chu

Genetics December 2016 204: 1377–1378



Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet

Ibrahim Ömer Çiçek, Samir Karaca, Marko Brankatschk, Suzanne Eaton, Henning Urlaub, and Halyna R. Shcherbata

Genetics March 2016 202:1167–1183



Multitasking of the piRNA Silencing Machinery: Targeting Transposable Elements and Foreign Genes in the Bdelloid Rotifer Adineta vaga

Fernando Rodriguez and Irina R. Arkhipova

Genetics May 2016 203:255–268



Genetical Genomics of Behavior: A Novel Chicken Genomic Model for Anxiety Behavior

Martin Johnsson, Michael J. Williams, Per Jensen, and Dominic Wright

Genetics January 2016 202: 327–340



Genome-Wide Structural Variation Detection by Genome Mapping on Nanochannel Arrays

Angel C. Y. Mak, Yvonne Y. Y. Lai, Ernest T. Lam, Tsz-Piu Kwok, Alden K. Y. Leung, Annie Poon, Yulia Mostovoy, Alex R. Hastie, William Stedman, Thomas Anantharaman, Warren Andrews, Xiang Zhou, Andy W. C. Pang, Heng Dai, Catherine Chu, Chin Lin, Jacob J. K. Wu, Catherine M. L. Li, Jing-Woei Li, Aldrin K. Y. Yim, Saki Chan, Justin Sibert, Željko Džakula, Han Cao, Siu-Ming Yiu, Ting-Fung Chan, Kevin Y. Yip, Ming Xiao, and Pui-Yan Kwok

Genetics January 2016 202: 351–362



A Delicate Balance Between Repair and Replication Factors Regulates Recombination Between Divergent DNA Sequences in Saccharomyces cerevisiae

Ujani Chakraborty, Carolyn M. George, Amy M. Lyndaker, and Eric Alani

Genetics February 2016 202: 525–540



Rapid Short-Read Sequencing and Aneuploidy Detection Using MinION Nanopore Technology

Shan Wei and Zev Williams

Genetics January 2016 202: 37–44



Hubby and Lewontin on Protein Variation in Natural Populations: When Molecular Genetics Came to the Rescue of Population Genetics

Brian Charlesworth, Deborah Charlesworth, Jerry A. Coyne, and Charles H. Langley

Genetics August 2016 203: 1497–1503



Natural Selection and Genetic Diversity in the Butterfly Heliconius melpomene

Simon H. Martin, Markus Möst, William J. Palmer, Camilo Salazar, W. Owen McMillan, Francis M. Jiggins, and Chris D. Jiggins

Genetics May 2016 203: 525–541


Effects of Linked Selective Sweeps on Demographic Inference and Model Selection

Daniel R. Schrider, Alexander G. Shanku, and Andrew D. Kern

Genetics November 2016 204: 1207–1223



Local Joint Testing Improves Power and Identifies Hidden Heritability in Association Studies

Brielin C. Brown, Alkes L. Price, Nikolaos A. Patsopoulos, and Noah Zaitlen

Genetics July 2016 203: 1105–1116



The Evolutionary Origin and Genetic Makeup of Domestic Horses

Pablo Librado, Antoine Fages, Charleen Gaunitz, Michela Leonardi, Stefanie Wagner, Naveed Khan, Kristian Hanghøj, Saleh A. Alquraishi, Ahmed H. Alfarhan, Khaled A. Al-Rasheid, Clio Der Sarkissian, Mikkel Schubert, and Ludovic Orlando

Genetics October 2016 204: 423-424


A Bibliometric History of the Journal GENETICS

Natalie Telis, Benjamin V. Lehmann, Marcus W. Feldman, and Jonathan K. Pritchard

Genetics December 2016 204: 1337–1342


Commonalities in Development of Pure Breeds and Population Isolates Revealed in the Genome of the Sardinian Fonni’s Dog

Dayna L. Dreger, Brian W. Davis, Raffaella Cocco, Sara Sechi, Alessandro Di Cerbo, Heidi G. Parker, Michele Polli, Stefano P. Marelli, Paola Crepaldi, and Elaine A. Ostrander

Genetics October 2016



Whole Genome Sequence of Two Wild-Derived Mus musculus domesticus Inbred Strains, LEWES/EiJ and ZALENDE/EiJ, with Different Diploid Numbers

Andrew P. Morgan, John P. Didion, Anthony G. Doran, James M. Holt, Leonard McMillan, Thomas M. Keane, and Fernando Pardo-Manuel de Villena

G3: Genes|Genomes|Genetics December 2016 6:4211–4216



A Forward Genetic Screen for Molecules Involved in Pheromone-Induced Dauer Formation in Caenorhabditis elegans

Scott J. Neal, JiSoo Park, Danielle DiTirro, Jason Yoon, Mayumi Shibuya, Woochan Choi, Frank C. Schroeder, Rebecca A. Butcher, Kyuhyung Kim, and Piali Sengupta

G3: Genes|Genomes|Genetics May 2016 6:1475–1487



Dynamics of Dark-Fly Genome Under Environmental Selections

Minako Izutsu, Atsushi Toyoda, Asao Fujiyama, Kiyokazu Agata, and Naoyuki Fuse

G3: Genes|Genomes|Genetics February 2016 6:365-376


Combinatorial Cis-regulation in Saccharomyces Species

Aaron T. Spivak and Gary D. Stormo

G3: Genes|Genomes|Genetics March 2016 6: 653–667


Preparing for Winter: The Transcriptomic Response Associated with Different Day Lengths in Drosophila montana

Darren J. Parker, Michael G. Ritchie, and Maaria Kankare

G3: Genes|Genomes|Genetics May 2016 6:1373–1381


Transcriptome Analysis Reveals that Vitamin A Metabolism in the Liver Affects Feed Efficiency in Pigs

Yunxia Zhao, Ye Hou, Fei Liu, An Liu, Lu Jing, Changzhi Zhao, Yu Luan, Yuanxin Miao, Shuhong Zhao, and Xinyun Li

G3: Genes|Genomes|Genetics November 2016 6:3615–3624


The Mouse Universal Genotyping Array: From Substrains to Subspecies

Andrew P. Morgan, Chen-Ping Fu, Chia-Yu Kao, Catherine E. Welsh, John P. Didion, Liran Yadgary, Leeanna Hyacinth, Martin T. Ferris, Timothy A. Bell, Darla R. Miller, Paola Giusti-Rodriguez, Randal J. Nonneman, Kevin D. Cook, Jason K. Whitmire, Lisa E. Gralinski, Mark Keller, Alan D. Attie, Gary A. Churchill, Petko Petkov, Patrick F. Sullivan, Jennifer R. Brennan, Leonard McMillan, and Fernando Pardo-Manuel de Villena

G3: Genes|Genomes|Genetics February 2016 6:263–279


Seizure Suppression by High Temperature via cAMP Modulation in Drosophila

Arunesh Saras and Mark A. Tanouye

G3: Genes|Genetics|Genomies October 2016 6:3381-3387


Novel Heterotypic Rox Sites for Combinatorial Dre Recombination Strategies

Katherine Chuang, Eileen Nguyen, Yuri Sergeev, and Tudor C. Badea

G3: Genes|Genomes|Genetics March 2016 6:559-571


Fine-Scale Crossover Rate Variation on the Caenorhabditis elegans X Chromosome

Max R. Bernstein and Matthew V. Rockman

G3: Genes|Genomes|Genetics June 2016 6: 61767–1776


Effects of DNA Methylation and Chromatin State on Rates of Molecular Evolution in Insects

Karl M. Glastad, Michael A. D. Goodisman, Soojin V. Yi, and Brendan G. Hunt

G3: Genes|Genomes|Genetics February 2016 6:357–363


The Effects of Both Recent and Long-Term Selection and Genetic Drift Are Readily Evident in North American Barley Breeding Populations

Ana M. Poets, Mohsen Mohammadi, Kiran Seth, Hongyun Wang, Thomas J. Y. Kono, Zhou Fang, Gary J. Muehlbauer, Kevin P. Smith, and Peter L. Morrell

G3: Genes|Genomes|Genetics March 2016 6:609-622


Canopy Temperature and Vegetation Indices from High-Throughput Phenotyping Improve Accuracy of Pedigree and Genomic Selection for Grain Yield in Wheat

Jessica Rutkoski, Jesse Poland, Suchismita Mondal, Enrique Autrique, Lorena González Pérez, José Crossa, Matthew Reynolds, and Ravi Singh

G3: Genes|Genomes|Genetics September 2016 6:2799–2808


A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function

Sebastian Wissel, Anja Kieser, Tetsuo Yasugi, Peter Duchek, Elisabeth Roitinger, Joseph Gokcezade, Victoria Steinmann, Ulrike Gaul, Karl Mechtler, Klaus Förstemann, Jürgen A. Knoblich, and Ralph A. Neumüller

G3: Genes|Genomes|Genetics August 2016 6:2467–2478


Genomic Access to Monarch Migration Using TALEN and CRISPR/Cas9-Mediated Targeted Mutagenesis

Matthew J. Markert, Ying Zhang, Metewo S. Enuameh, Steven M. Reppert, Scot A. Wolfe, and Christine Merlin

G3: Genes|Genomes|Genetics April 2016 6:905–915


Whole Genome Comparison Reveals High Levels of Inbreeding and Strain Redundancy Across the Spectrum of Commercial Wine Strains of Saccharomyces cerevisiae

Anthony R. Borneman, Angus H. Forgan, Radka Kolouchova, James A. Fraser, and Simon A. Schmidt

G3: Genes|Genomes|Genetics April 2016 6:957–971


rDNA Copy Number Variants Are Frequent Passenger Mutations in Saccharomyces cerevisiae Deletion Collections and de Novo Transformants

Elizabeth X. Kwan, Xiaobin S. Wang, Haley M. Amemiya, Bonita J. Brewer, and M. K. Raghuraman

G3: Genes|Genomes|Genetics September 2016 6: 2829–2838



A Pedigree-Based Map of Recombination in the Domestic Dog Genome

Christopher L. Campbell, Claude Bhérer, Bernice E. Morrow, Adam R. Boyko and Adam Auton

G3: Genes|Genomes|Genetics 6: 3517–3524


Functional Genetic Screen to Identify Interneurons Governing Behaviorally Distinct Aspects of Drosophila Larval Motor Programs

Matt Q. Clark, Stephanie J. McCumsey, Sereno Lopez-Darwin, Ellie S. Heckscher and Chris Q. Doe

G3: Genes|Genomes|Genetics 6: 2023–2031


Estimating Trait Heritability in Highly Fecund Species

Sarah W. Davies, Samuel V. Scarpino, Thanapat Pongwarin, James Scott and Mikhail V. Mat

G3: Genes|Genomes|Genetics 5: 2639–2645


Sequential Turnovers of Sex Chromosomes in African Clawed Frogs (Xenopus) Suggest Some Genomic Regions Are Good at Sex Determination

Benjamin L. S. Furman, Ben J. Evans

G3: Genes|Genomes|Genetics 6: 3625-3633