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Science & Publishing
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Science & Publishing
Old Transposable Elements, New Tricks
Transposable elements don’t proliferate in genomes at a steady pace; they often arrive in bursts. But models of neutral TE evolution assume transposition occurs at a constant rate. That makes it harder to test, for instance, whether low TE allele frequencies in a population are due to negative selection or just a recent transposition burst.…
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Science & Publishing
Assembling a Colossus
The loblolly pine genome is big. Bloated with retrotransposons and other repetitive sequences, it is seven times larger than the human genome and easily big enough to overwhelm standard genome assembly methods. This forced the loblolly pine genome sequencing team, led by David Neale at the University of California, Davis, to look for ways to…