Science & Publishing

Well over 15,000 years ago, a man and a bear died in a cave in the Jura Mountains in modern-day Switzerland. That was the end of the story for millennia—until their remains were discovered in 1954 by researchers investigating the cave. Further work in the 1990s uncovered the fact that the man had, in fact,…

To boost transcription of a target gene, enhancer sequences must make contact with the gene’s promoter. This crucial meeting is mediated by interacting proteins and the formation of chromatin loops that bring distant enhancers and promoters together. Although it’s clear that enhancers increase transcription this way, the primary mechanisms by which an enhancer’s target genes…

Check out the January issue of G3! Table of Contents Investigations The CgHaa1-Regulon Mediates Response and Tolerance to Acetic Acid Stress in the Human Pathogen Candida glabrata Ruben T. Bernardo, Diana V. Cunha, Can Wang, Leonel Pereira, Sónia Silva, Sara B. Salazar, Markus S. Schröder, Michiyo Okamoto, Azusa Takahashi-Nakaguchi, Hiroji Chibana, Toshihiro Aoyama, Isabel Sá-Correia,…

Check out the January issue of GENETICS by looking at the highlights or the full table of contents! ISSUE HIGHLIGHTS This Month’s Centennial Articles The sustained impact of model organisms—in genetics and epigenetics, pp. 1-4 Nancy M. Bonini and Shelley L. Berger In this GENETICS Centennial commentary, Nancy M. Bonini and Shelley L. Berger reflect on the history of…

These worms are as long as a pencil’s tip and only just visible without a microscope. They are among the smallest multicellular animals, but they still have complex organ systems. They are Caenorhabditis elegans, one of the most important organisms in modern biology and a key to understanding the most basic molecular processes of life.…

Towering sugar pine trees dominate the mountain forests of California and Oregon. They are the tallest pine trees in the world, regularly growing to skyscraper heights of over 100 meters. But these forest behemoths are under attack from a very tiny foe: an invasive fungus. White pine blister rust was accidentally introduced to western North…

Do you have whole genome sequence (WGS) data burning a hole in your pocket? Many high-quality WGS datasets languish unpublished and undescribed because they may not always—in isolation—reveal substantial new biological insights. However, the editors of G3: Genes|Genomes|Genetics recognize that WGS data on strain variation, comparative analysis of different model organism species, and other rich…

Each year, emergency departments in the US treat almost 700,000 people for traumatic brain injury (TBI). The outcome depends largely on the severity and location of the injury, but these aren’t the only factors. Age also plays a role, with children often recovering more fully than do adults. The patient’s diet following the injury may…

Symptoms of schizophrenia most commonly begin to creep up in young adulthood. Although genetics play a major role in this complex disorder, narrowing down the search for the genes involved has proven frustratingly difficult. Risk loci identified by genome-wide association studies (GWAS) may contain several genes, making it unclear which of these contribute to pathology.…

Check out the December issue of GENETICS by looking at the highlights or the full table of contents! ISSUE HIGHLIGHTS This Month’s Centennial Articles Edward East on the Mendelian basis of quantitative trait variation, pp. 1321-1323 Michael Turelli Reviews editor Michael Turelli introduces Edward East’s 1916 Classic on the Mendelian basis of a continuously varying phenotype. This work exquisitely…

Check out the December issue of G3! Table of Contents Meeting Report Meeting Report: The Allied Genetics Conference 2016 Organizers of The Allied Genetics Conference 2016 G3 December 2016 6:3765-3786; doi:10.1534/g3.116.036848 Full Text | Full Text (PDF) Investigations Assessing the Gene Content of the Megagenome: Sugar Pine (Pinus lambertiana) Daniel Gonzalez-Ibeas, Pedro J. Martinez-Garcia, Randi…